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Effective infection control efforts are essential in preventing nosocomial transmission of TB. A hierarchy of control measures is recommended to prevent TB transmission in health care facilities.
-- Administrative controls are most important and include measures to reduce the risk of exposure to persons with - infectious TB; this includes careful screening, early identification and treatment of patients with TB. A high - index of suspicion is critical. Patients with or at risk for TB need to be isolated upon admission (placed in a - negative pressure airborne infection isolation [AII] room). Unsuspected patients with active TB disease and - misdiagnosis (especially among HIV-infected patients who may have “atypical” or non-classical presentations) - have led to nosocomial transmission at a number of hospitals (as well as at correctional institutions and other - health care facilities).
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+ Administrative controls are most important and include measures to reduce the risk of exposure to persons with infectious TB; this includes careful screening, early identification and treatment of patients with active TB disease.
+ A high index of suspicion is critical.⌃ +Grady Memorial Hospital in Atlanta has prevented nosocomial transmission in large part by the effective use of administrative controls. Careful screening of patients and isolation of those at risk for TB have been accomplished by the introduction of an expanded respiratory isolation policy.
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In general, the risk of occupational acquisition of TB is low among the large majority of US health care workers - (HCWs) given the changing epidemiology of the disease in the U.S. The risk of TB exposure among most US-based - health care workers (HCWs) is similar to the general population given the decreased TB incidence and improved - hospital infection control measures in this country. Given the low risk among the vast majority of US HCWs, - serial TB testing for US-based HCWs has been associated with a high rate of false-positive conversions. - Therefore, CDC guidelines were updated in 2019 and no longer recommend routine serial testing for most US-based - HCWs [MMWR Morb Mortal Wkly Rep 2019;68:439–44.]. Guidelines continue to recommend baseline screening and - testing in addition to an individual TB risk assessment to aid in TB test interpretation. All HCWs should have - baseline test for LTBI (unless documented to be previously TST or IGRA positive or documented to have had prior - TB disease). Two-step tuberculin skin testing upon employment is recommended unless the HCW had a TST in the - prior year. Updated guidelines suggest health care facilities may consider serial testing in selected - situations, such professionals at increased risk for exposure or selected areas in the facility where - transmission has occurred and/or infection control lapses occur and infectious patients were present. If serial - testing of HCWs is needed, we recommend the use of the TST rather than an IGRA for reasons described above (see - pages 19—21 ). HCWs should be educated about the basic concepts of TB transmission and pathogenesis, infection - control practices, signs and symptoms of TB, and risk for TB exposure in the facility annually.
-- Following exposure, HCWs should be evaluated for signs and symptoms of TB. Those with a negative baseline test - and no prior LTBI or TB should have a TST (or IGRA) performed. If the test is negative, a repeat test 8-10 weeks - after the last exposure is recommended.
-+ (HCWs) given the changing epidemiology of the disease in the U.S.
++ The risk of TB exposure among most US-based health care workers (HCWs) is similar to the general population given the decreased TB incidence and improved hospital infection prevention and control measures in the U.S. +
+Given the low risk among the vast majority of US HCWs, serial TB testing for US-based HCWs has been associated with a high rate of false-positive conversions. Therefore, CDC guidelines were updated in 2019 and no longer recommend routine serial testing for most US-based HCWs [MMWR Morb Mortal Wkly Rep 2019;68:439–44.]. Guidelines continue to recommend baseline screening and testing in addition to an individual TB risk assessment to aid in LTBI diagnostic test interpretation.
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+ All HCWs should have baseline test for LTBI (unless documented to be previously TST or IGRA positive or documented to have had prior TB disease). If the TST is used, two-step tuberculin skin testing upon employment is recommended unless the HCW had a TST in the prior year.
+ +Updated guidelines suggest health care facilities may consider serial testing in selected situations, such professionals at increased risk for exposure or selected areas in the facility where transmission has occurred and/or infection control lapses occur and infectious patients were present.
+ ++ If serial testing of HCWs is needed, we recommend the use of the TST rather than an IGRA because of high rates of false positive IGRA tests when serial testing of low risk US health care workers was performed as described above (see pages 19—21 ). +
+ ++ Following a TB exposure from a patient with infectious TB not in Airborne Infection Isolation Precautions, HCWs should be evaluated for signs and symptoms of TB. Those with a negative baseline test and no prior LTBI or TB should have a TST (or IGRA) performed. If the test is negative, a repeat test 8-10 weeks after the last exposure is recommended.
+Any worker who develops symptoms of active TB disease or whose test for LTBI (TST or IGRA) converts to positive should be evaluated promptly. Health care workers with recent TB infection on the basis of a conversion to a positive test for LTBI (regardless of age) and no evidence of active disease should be encouraged to take @@ -46,7 +46,7 @@
| Grady Hospital TB Isolation Policy | +Grady Hospital TB Isolation Policy |
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